Cyclodehydratases
WebF protein-dependent cyclodehydratase Recent work from our group 36 has revealed the dependence of truncated cyclodehydratases found in thiopeptide 3 and … WebApr 16, 2024 · In contrast, the cyclodehydratases are considerably more sequence divergent. Notably, despite the greater sequence diversity among putative cyclodehydratases, the Pro-rich C-termini (defined as two or more Pro residues in the last 10 residues) are present in ~90% of proteins across all clades, consistent with a potential …
Cyclodehydratases
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Carbohydrase is the name of a set of enzymes that catalyze 5 types of reactions, turning carbohydrates into simple sugars, from the large family of glycosidases. Carbohydrases are produced in the pancreas, salivary glands and small intestine, breaking down polysaccharides. This is because complex sugars are often insoluble (such as starch), and therefore breaking them down will make it easier for the sugars to be absorbed into the blood, t… WebJan 21, 2014 · Thiazoles and oxazoles are installed by the successive action of an ATP-dependent cyclodehydratase (C- and D-protein) and a FMN-dependent dehydrogenase (B-protein), which are responsible for azoline formation and azoline oxidation, respectively.
WebFeb 20, 2024 · Noun [ edit] cyclodehydratase ( plural cyclodehydratases ) ( biochemistry) A cyclic dehydratase. This page was last edited on 20 February 2024, at 20:24. Text is … WebApr 1, 2024 · Cyclases, such as lanthionine synthetases, cyclodehydratases, ATP-grasp ligases, and various other families of macrocyclases, generally tolerate a wide variety of sequence contexts and have been the most often-applied modification enzymes to randomized peptide libraries [2].
WebFeb 27, 2009 · As exemplified by phylogenetic analysis of the thiopeptide cyclodehydratases, they are distinct from the polythiazole synthetases in both bacteriocin and cyanobactin biosynthesis ( Li et al., 1996, Donia et al., 2006, Lee et al., 2008, Walsh and Nolan, 2008) ( Figure S3 ). Web1.6 Characterization of RiPP cyclodehydratases. 1.6.1 Functional dissection of the cyclodehydratase. 1.6.1.1 YcaO protein. After the pioneering studies on the microcin B17 …
WebApr 8, 2011 · Radical SAM enzymes with this additional domain, as detected by TIGR04085, significantly outnumber lantibiotic synthases and cyclodehydratases combined in reference genomes while being highly enriched for members …
WebAnti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment by Sergey Zotchev 15 Biology , Fungi , Medicine , Multidisciplinary Utilization of n-alkanes by a newly isolated strain of Acinetobacter venetianus: the role of two AlkB-type alkane hydroxylases hometown buffet napa caWebJan 24, 2024 · The modification enzyme ATP-dependent cyclodehydratase acts on the precursor peptides and catalyzes the formation of thiazoline and methyloxazoline rings from Cys and Thr residues, respectively, and their subsequent oxidation by FMN-dependent dehydrogenase converts the resulting thiazoline and methyloxazoline rings to their … hometown buffet national cityWebThe oxidation (dehydrogenation) of thiazoline to thiazole is common in natural products, especially in RiPPs. 543, 546 The tendency for RiPP BGCs to install thiazoles may … his girl friday 123moviesWebRibosomally synthesized and post-translationally modified peptides (RiPPs) are peptide-derived natural products that include the FDA-approved analgesic ziconotide1,2 as well as compounds with... hometown buffet national city hoursWebRibosomally synthesized and post-translationally modified peptides (RiPPs) are peptide-derived natural products that include the FDA-approved analgesic ziconotide1,2 as well as compounds with... hometown buffet mt washington kyWebThe meaning of CYCLODEHYDRATION is cyclization involving chemical dehydration. Love words? You must — there are over 200,000 words in our free online dictionary, but you … his girl friday 1940 plotDehydratases are a group of lyase enzymes that form double and triple bonds in a substrate through the removal of water. They can be found in many places including the mitochondria, peroxisome and cytosol. There are more than 150 different dehydratase enzymes that are classified into four groups. Dehydratases can act on hydroxyacyl-CoA with or without cofactors, and some have a metal and non-metal cluster act as their active site. his girl friday 1940 quotes