Doxofylline solubility
WebApr 2, 2024 · The solid-liquid phase equilibrium solubility of Doxofylline was measured and discussed in ten pure organic solvents and co-solvent mixtures of acetonitrile + … WebAug 1, 2024 · The mole-fraction solubility of doxofylline in four blends of isopropanol + water, ethanol + water, acetone + water and methanol + water covering the temperature from 278.15 to 323.15 K was acquired by the use of saturation shake-flask method under atmospheric pressure of 101.2 kPa.
Doxofylline solubility
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WebSep 1, 2024 · Crystallization and purification is an important step in drug preparation. In this work, the solubility of doxofylline in some pure and mixed solvents at T = 273.15–313.15 K was experimentally determined under 101.2 kPa.Infrared spectroscopy (IR) was used to evaluate the crystal form of doxofylline, and no solvates or new form formation were … WebThis patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results.
WebSolubility: Soluble in DMSO Shelf Life: >2 years if stored properly Drug Formulation: This drug may be formulated in DMSO Stock Solution Storage: 0 - 4 C for short term (days to … Webto three times in a day. Doxofylline is coming under class III of BCS classification and well absorbed orally. It is having solubility of 12 mg/ml in water and having PKa 9.87[2]. The present studies were carried on the formulation and evaluation of sublingual tablets of Doxofylline using super disintegrant like sodium starch glycolate
WebThe newly prepared novel crystal form (Form P) of Doxofylline with rod shape morphology is more suitable in Doxofylline manufacturing. INTRODUCTION: Doxofylline is chemically 7-(1, 3 - Dioxolan-2-ylmethyl)- 1, 3-dimethylpurine-2, 6-dione is a Xanthine derivative drug used in the treatment of Asthma 1. The molecular formula is C 11 H 14 N 4 0 4 WebAug 1, 2024 · The mole-fraction solubility of doxofylline in four blends of isopropanol + water, ethanol + water, acetone + water and methanol + water covering the temperature …
WebDec 4, 2013 · DOXOFYLLINE. LAUNCHED 1987, Istituto Biologico Chemioterapico ABC. 69975-86-6 CAS NO. 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione ... Generally, the solubility of methylxanthines …
WebIn this work, the solubility of doxofylline in some pure and mixed solvents at T = 273.15–313.15 K was experimentally determined under 101.2 kPa. Infrared spectroscopy (IR) was used to evaluate... long lake cafeWebApr 2, 2024 · Solubility and Model Correlation of Doxofylline in Pure Solvents at the Temperature Range of 283.15–323.15 K. Doxofylline (DFL) is a theophylline … long lake by snowmobileWebAug 23, 2012 · 1. the doxofylline compound of a kind of high-dissolvability shown in the formula I, It is characterized in that: its spacer is Cc; Unit cell parameters: ° γ=90.00, α=90.00 °, z=4. 2.... long lake camp adventures reviewsWebDoxofylline (Doxophylline) is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Quality confirmed by NMR & HPLC. See customer reviews, validations & product citations. ... Solubility (25°C) In vitro. Chemical Information. Molecular Weight: 266.25: Formula: C 11 H 14 N 4 O 4. CAS No. 69975-86-6: Storage: 3 years-20°C ... long lake cabin rentals michiganWebSolubility: ≥ 2.5 mg/mL (9.39 mM); Clear solution 3. Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: ≥ 2.5 mg/mL (9.39 mM); Clear solution 4. … hoover wet carpet vacuum cleanerhoover weight loss clinicWebCHARACTERIZATION OF SERTRALINE & DOXOFYLLINE Solubility of Sertraline The solubility of drug sample was determined according to I.P. 1996.[38] Two 10 ml and one 250 ml volumetric flasks were taken. Flask 1: 10 mg of Sertraline was accurately weighed and transferred to 10 ml volumetric flask. 0.1 ml of water was added into it. long lake by itasca state park mn