Grb2 molecular weight
WebMolecular Weight of GRB2: 25-31 kDa. Positive Controls: COLO 320DM cell lysate: sc-2226, NIH/3T3 whole cell lysate: sc- 2210 or A-431 whole cell lysate: sc-2201. STORAGE Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. WebJun 24, 2015 · The adaptor protein growth factor receptor-bound protein 2 (Grb2) is ubiquitously expressed in eukaryotic cells and involved in a multitude of intracellular protein interactions. Grb2 plays a pivotal role in tyrosine kinase-mediated signal transduction including linking receptor tyrosine kinases to …
Grb2 molecular weight
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Web蛋白分子量 predicted molecular weight：39kDa 性 状 Lyophilized or Liquid 免 疫 原 KLH conjugated synthetic peptide derived from human SH3GL3 (121-220aa) 亚 型 IgG 纯化方法 affinity purified by Protein A 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 WebGRB2 is a 217 amino acid protein with predicted and observed molecular mass of ~25 kD. Distribution Tissue Distribution: Ubiquitously expressed Cellular Distribution: Plasma …
WebThe single MAP2 gene produces four major transcripts producing four proteins, MAP2A, MAP2B, MAP2C and MAP2D. MAP2A and MAP2B are very high molecular weight proteins, with apparent molecular weight on SDS-PAGE about 250kDa, while MAP2C and MAP2D are much lower molecular weight forms with apparent SDS-PAGE size about … WebLane 1 : Anti-GRB2 antibody (ab2234) at 0.05 µg/ml Lane 2 : Anti-GRB2 antibody (ab2234) at 0.05 µg Lane 1 : Human thymus tissue lysate in RIPA buffer Lane 2 : MOLT4 cell …
WebJoo et al. found that NoxO1 was highly expressed in colon cancer tissues. After the knockout of this gene, the growth of tumor tissues was inhibited, and NOX1 activity as well as ROS production were regulated by GRB2/CBI-mediated NoxO1 proteolysis. The activity of NADPH oxidase (NOx) is regulated by NoxO1. WebRecombinant Human GRB2, derived from the transfected human HEK293 cells
WebApr 29, 2014 · As shown in Figure 1 D, the SUMO1-GST-Grb2 with higher molecular weight of approximately 70 kDa was detected in the E.coli transformed with pE1E2S1 …
WebJul 13, 2024 · Grb2 has been discovered to form complexes with a range of cellular proteins and o have roles in cell growth, cell proliferation, metabolism, embryogenesis, and cancer cell differentiation [ 4, 5... how to open a dbf in excelWebNov 29, 1996 · The Grb2 SH2 domain binds to Tyr1068 of EGFR and Tyr317 of Shc while its SH3 domains bind to mSos1. Therefore, EGF treatment potentially results in the formation of several multimeric signaling complexes, including EGFR-Grb2-mSos1, EGFR-Shc-Grb2-mSos1, and Shc-Grb2-mSos1, linking the receptor to activation of the Ras … how to open a db file in windowsWebThe molecular weight of Grb2 is 25,206.35 Da, and the theoretical isoelectric point of the protein, as calculated using the molecular database ExPASy, is 5.89 (10). The protein is … mural look on buffetWebMar 20, 2024 · It is a large protein; the molecular weight for human vinculin is 117 kDa with 1066 amino acids. It can be used as a loading control for high molecular weight proteins. In muscle tissues, a splice variant with an extra exon with the molecular weight of 150 kDa is also expressed. Nuclear proteins - nuclear loading controls Lamins muralo company inc. theWebJul 18, 2024 · By using the Rad51 antibody after chemical cross-linking, a band of relatively high molecular weight (ca. 119 kDa; approximate to the sum of molecular weights for Rad51, PTEN, and Grb2) was ... mural lightsWebThe first genome-wide significant finding was reported for GAB2 (GRB2-associated binding protein 2) by Ref. 36. This finding has been met with mixed replications and currently … mural life manchesterWebThe GRB2 adaptor protein binds activated EGFR at phospho-Tyr1068 (9). A pair of phosphorylated EGFR residues (Tyr1148 and Tyr1173) provide a docking site for the Shc scaffold protein, with both sites involved in MAP … how to open a dbs file